You microneedle your face religiously. You apply growth factor serum within sixty seconds. You follow the protocol. Your facial skin has never looked better. Meanwhile your neck tells a different age story entirely — crepey texture, horizontal lines, sun-damaged décolletage that looks a decade older than the face sitting above it. The disconnect exists because most people never extend their microneedling protocol below the jawline, and those who do rarely apply the right microneedling body serum afterward. A randomized controlled trial confirmed that growth factors applied post-microneedling produced significant improvements after one session — results the control group needed four sessions to approach (PMC7716740). That biology does not change at the collarbone. It works identically on every area of skin that contains fibroblasts.
The right microneedling body serum converts body treatments from forgotten afterthought into structural transformation. Growth factors promote fibroblast migration, increase collagen and hyaluronic acid synthesis, and activate the PI3K/AKT and ERK/MAPK repair pathways (PMC10333026) — whether those fibroblasts sit in your cheek, your neck, your chest, or your thigh. Bradceuticals Gold Mesenchymal Stem Cell Growth Factor Serum delivers the complete human mesenchymal stem cell secretome through open microchannels anywhere on the body — applied to damp skin immediately after the final pass — the microneedling body serum that gives neglected areas the same collagen instruction your face has been receiving all along.
Area 1: Neck — Where Age Shows First and Gets Treated Last
The neck contains thinner dermis, fewer sebaceous glands, and less subcutaneous fat than the face — making it more vulnerable to collagen loss and more visible when that loss occurs. Horizontal necklace lines, vertical bands, and crepey texture announce your age before anyone looks at your face. Yet most skincare routines stop at the jawline.
A microneedling body serum containing growth factors addresses neck aging through the same mechanism that works on facial skin. Microchannels created by dermarolling the neck deliver growth factor proteins exceeding 15,000 daltons directly to dermal fibroblasts — the only route these large molecules have past the stratum corneum barrier. A 2025 narrative review confirmed that growth factors through microchannels augment collagen remodeling with new fibers persisting five to seven years (PMC11993440). Your neck deserves a microneedling body serum as much as your face deserves its post-procedure growth factors.
Area 2: Décolletage — Where Sun Damage Accumulates for Decades
The chest receives more cumulative UV exposure than almost any other body area — years of V-neck shirts, swimsuits, and forgotten sunscreen. The result is mottled pigmentation, deep crepey wrinkles, and solar elastosis that moisturizers cannot reverse because the damage lives in the dermis.
A microneedling body serum with EGF addresses décolletage photoaging on two fronts simultaneously. EGF inhibits pro-inflammatory cytokines that perpetuate UV-initiated degradation (PMC10333026), while TGF-beta and PDGF instruct fibroblasts to deposit new collagen where UV destroyed it. Clinical data showed that EGF reduced melanogenesis-associated protein expression with 73.4% melasma improvement (PMC8423211) — addressing both the structural damage and the pigmentation changes that make chest skin look decades older than it should.
Area 3: Upper Arms — Where Crepiness Reveals Lost Collagen
Crepey upper arm skin results from dermal thinning — the same collagen and elastin loss that causes facial aging, just in an area that rarely receives treatment. The upper arms have sufficient dermal thickness to respond well to microneedling, yet they are almost universally ignored in skincare protocols.
A microneedling body serum applied after dermarolling the upper arms delivers growth factors to fibroblasts in tissue that is starving for instruction. A 24-week trial demonstrated that continuous growth factor application produced biopsy-confirmed collagen, elastin, AND decorin increases (PMC9823186). Decorin is the proteoglycan that organizes collagen fibers into functional bundles — the difference between skin that feels firm and skin that just feels thick. Your microneedling body serum brings this same structural reorganization to arms that have been aging without intervention.
Area 4: Thighs and Abdomen — Where Stretch Marks Live
Stretch marks are dermal scars — torn collagen and elastin fibers that healed with disorganized scar tissue instead of normal lattice-pattern collagen. Microneedling breaks up this disorganized tissue and initiates a new healing cascade. The microneedling body serum you apply determines whether that new healing produces organized collagen or simply creates new scar tissue on top of old.
Growth factors instruct fibroblasts to deposit organized Collagen I — the permanent structural protein that replaces Collagen III wound-repair fibers during the remodeling phase. A 2025 RCT confirmed that even PDGF alone outperformed standard care on 6 of 7 parameters after microneedling (PMC12427151). Bradceuticals’ complete secretome delivers PDGF alongside EGF, FGF, TGF-beta, VEGF, and HGF plus exosomes — providing the full instruction set for organized collagen replacement in stretch-marked tissue.
Area 5: Hands — Where Aging Is Impossible to Hide
Hands show age through visible veins, thinning skin, age spots, and loss of volume — all consequences of dermal collagen loss and melanocyte dysregulation. A microneedling body serum applied after gentle dermarolling of the dorsal hands delivers growth factors to the thinnest, most exposed skin on your body.
MSC conditioned media from younger sources contains dramatically higher growth factor concentrations — bFGF 5x, HGF 8.19x higher — with stronger fibroblast proliferation and melanin inhibition (PMC12476799). This makes a quality microneedling body serum particularly effective for hands, where both collagen building and pigment correction are needed simultaneously.
The Body Protocol
Important: Bradceuticals Gold Mesenchymal Stem Cell Growth Factor Serum is a post-microneedling treatment serum — not a gliding serum. Use a sterile hyaluronic acid solution for device movement during active needling, then apply the growth factor serum immediately after.
Step 1: Dermaroll the target area with a 0.25-0.5mm roller using vertical, horizontal, and diagonal passes.
Step 2: Within 60 seconds, apply Bradceuticals Gold Mesenchymal Stem Cell Growth Factor Serum to damp skin. Pat gently.
Step 3: Layer fragrance-free moisturizer 5-10 minutes later.
First 48 hours: Continue twice-daily microneedling body serum application. Mineral sunscreen on exposed areas. No retinol, AHAs, or BHAs.
Between sessions: Apply growth factor serum to treatment areas morning and evening. Schedule sessions every four to six weeks. The RCT maintained continuous daily application (PMC7716740).
Results Timeline for Body Areas
Weeks 2-4: Texture smooths. Crepiness softens. Stretch marks begin fading from red/purple toward skin tone.
Weeks 4-8: Collagen remodeling firms treated areas. Neck lines soften. Décolletage wrinkles fill from below.
Months 3-6: Structural transformation visible. Stretch marks significantly less prominent. Hands look fuller. New collagen persists five to seven years (PMC11993440). Every session with the right microneedling body serum compounds permanently.
Frequently Asked Questions
Can I use the same microneedling body serum on my face? Yes — Bradceuticals Gold Mesenchymal Stem Cell Growth Factor Serum is formulated for all skin areas. The same growth factor biology works wherever fibroblasts reside.
What needle depth for body microneedling? 0.25-0.5mm for home use. Body skin is generally thicker than facial skin and tolerates dermarolling well. Consult a professional for deeper treatments.
Is a microneedling body serum safe for stretch marks? Yes — growth factors instruct organized collagen deposition that replaces disorganized scar tissue. Multiple sessions produce cumulative improvement.
How often should I use a microneedling body serum on my body? Dermaroll treatment areas every four to six weeks. Apply growth factor serum twice daily to treated areas between sessions.
References
- Merati M, et al. An Assessment of Microneedling with Topical Growth Factors. J Clin Aesthet Dermatol. 2020;13(11):22-27. (PMC7716740)
- Shin SH, et al. The use of epidermal growth factor in dermatological practice. Int Wound J. 2023;20(6):2414-2423. (PMC10333026)
- Tehrani L, et al. Physiological Mechanisms and Therapeutic Applications of Microneedling. Cureus. 2025;17(3):e80510. (PMC11993440)
- Miller-Kobisher B, et al. Epidermal Growth Factor in Aesthetics and Regenerative Medicine. J Cutan Aesthet Surg. 2021;14(2):137-146. (PMC8423211)
- Naughton GK, et al. Targeting Multiple Hallmarks of Skin Aging. Dermatol Ther. 2023;13(1):169-186. (PMC9823186)
- Lynch SE, et al. Recombinant Pure PDGF Improves Aesthetic Results Following RF Microneedling. J Cosmet Dermatol. 2025;24(9):e70425. (PMC12427151)
- Ahn H, et al. Efficacy and Safety of UCMSC-CM for Skin Aging. World J Stem Cells. 2025;17(9):108049. (PMC12476799)
Disclaimer: This article is for informational purposes only and does not constitute medical advice. Individuals with active skin cancer, pre-cancerous lesions, or a history of skin malignancy should consult a board-certified dermatologist before using any growth factor product. Consult a qualified healthcare provider before beginning any microneedling protocol. Body microneedling at depths greater than 0.5mm should be performed by licensed professionals. Individual results may vary.
Last Reviewed: April 2026
About Bradceuticals : Thuy Myers is the founder of Bradceuticals which manufactures and distributes skin care and hair regrowth serums that use growth factors from human stem cells as the catalyst for regeneration. When she is not busy running the business and maintaining blogs, she is continuing her practice as a semiconductor engineer and occasionally teaches college engineering. In her free time, she enjoys visiting the beach with her MUCH better half, working out at the gym, and hanging out with her kiddo.